"I believe there’s a lot of stage-setting for the next film," Giamatti tells MTV. "There are several villains in this movie, and some of them are more foreground and important. Jamie Foxx [Electro] is and stuff. A couple of us are more hanging around the background because I think there will be a bigger deal... I don’t actually know [if The Sinister Six is the plan], but that seems to be what they’re doing. I’m not an idiot either, but I can’t claim hard and fast knowledge of this. I won’t. I can’t because I don’t actually know, but you and I can speculate."
It is of course not the first time that The Sinister Six has been teased for Sony's Spidey universe (see this production photo featuring producer Avi Arad, for starters), and with The Amazing Spider-Man 2 set to feature the likes of Norman Osborn (Chris Cooper) and Harry Osborn (Dane DeHaan) alongside Electro and The Rhino - not to mention rumoured appearances from The Vulture, Black Cat, and even Carnage - then like Giamatti says it certainly seems plausible that we'll get to see Spidey's foes teaming up at some point in the next two movies.