Jason Statham
The star of films such as The Transporter,The Italian Job,Crank,War and The Expendables has that perfect balance of rugged good looks and kick ass fighting skills that you would want out of James Bond. Who needs suave when you can beat a man to death with his bare hands and we all know that Statham wouldn't have any problem getting any on screen Bond girl that he wanted.
David Tennant
Doctor Who fan girls, and boys, would certainly flock to any Bond film starring the 10th Doctor. Tennant already had a pseudo-Bond look during his stint as the Doctor and Tennant would actually bring a bit of range in regards to acting to the part. Tennant is handy with a sword and a sonic screwdriver, but can we get used to seeing the Doctor with a gun?
Shermar Moore
Is the world ready for a black James Bond? If so, then Shermar Moore could certainly fit the part. Already known for his part of Derek Morgan on Criminal Minds, Moore already had the good looks and can certainly pull off the charm needed to make the Bond girls swoon. In addition, he would be the perfect for the action and fighting sequences needed. If Will Smith can play Jim West, why can't Shermar Moore play James Bond.
Hugh Laurie
Paging Dr. Bond! Laurie became a superstar with his role of Dr. Gregory House and proved that he has the range needed to pull off Bond. Cleaned up, the Oxford native has the right mix of charm and class needed to pull of the role. The question remains whether he has the ability to pull of the big fight scenes needed to be James Bond.